Therapies Include:
- Alpha-1
- Biologics
- Biosimilars
- Enzyme Replacement Therapies
- Immunoglobulins
Patients come first at Infusion for Health. Your care, safety, and comfort are at the center of everything we do.
We started Infusion for Health because patients who need routine infusions deserve a better setting than the impersonal and inconvenient hospital infusion center.
WHO WE TREAT
We’ve tailored your entire experience for patients with complex, chronic conditions in mind. You receive high-quality care in a more comfortable, relaxing environment. Our personalized service, private infusion suites, and continuous monitoring by our medical team helps patients manage their autoimmune conditions.
Our compassionate, experienced infusion nurses treat a range of autoimmune disorders and other conditions including:
- Alpha-1 Antitrypsin Deficiency
- Alzheimer’s/Dementia
- Anemia
- Asthma
- Chronic inflammatory demyelinating polyneuropathy (CIDP)
- Gout
- hATTR Amyloidosis
- High Cholesterol
- Immune Deficiency Disorders
- Inflammatory Bowel Disease (IBD)
- Lupus
- Migraines
- Multiple Sclerosis
- Myasthenia Gravis
- Plaque Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Thyroid Eye Disease
- Urticaria
Please contact us if you receive routine infusions for another condition that you don’t see on this list
Therapies We Offer
Infusion for Health is one of the leading providers of adult and pediatric infusion services, and we offer a wide range of infusion therapies. We administer over 45 brands and biosimilars pharmaceuticals and biologics from US-based suppliers. Additionally, we monitor new drug approvals to ensure that our patients have access to the broadest range of infused therapies available.
Injection Treatments
Amvuttra
Amvuttra was created for people who suffer from hereditary ATTR (hATTR) amyloidosis. By taking this medication, patients can achieve a significant improvement in nerve function and their overall quality of life. In addition, this medication only has to be taken once every three months.
hATTR amyloidosis is a progressive condition that happens because of a mutation in the transthyretin (TTR) gene. This rare disorder can negatively impact the nerves, heart, and digestive system. In addition, some people may suffer from blurred vision, kidney dysfunction, and glaucoma.
Amvuttra can help by reducing the amount of TTR protein your liver makes. As a result, your amyloid deposits are decreased. This can lead to fewer polyneuropathy symptoms.
Every three months, you will receive Amvuttra as a subcutaneous injection. It can be given in your thighs, upper arm, or abdomen. Although it can occasionally reduce your vitamin A levels, no premedications or lab work are generally required before taking Amvuttra.
Apretude
You can take Apretude to prevent human immunodeficiency virus (HIV). Currently, Apretude is the only long-acting PrEP you can inject for decreasing your chances of getting HIV. Instead of having to take a pill each day, you can get an injection every other month.
You will start by getting two injections a month apart. Afterward, you can take as few as six doses of Apretude each year. Because the medicine is slowly released into your body over time, your body is able to keep a stable level of medication between your injections.
You should never take this medication if you are already infected with HIV. Sometimes, HIV tests don’t pick up a recent infection. If you are experiencing symptoms of HIV, it is important to get tested again.
Before you start taking Apretude, you should talk to your doctor about whether this medication is right for you. Your doctor will also give you a new HIV test before each appointment to see if you are still HIV negative. If you have any side effects from taking the medication, you should discuss them with your healthcare provider.
Asceniv
Asceniv consists of immune globulin. It is made for adults and teenagers between the ages of 12 and 17. If you suffer from primary immunodeficiency, Asceniv can help you fight off potential infections.
Each dose of Asceniv is created from human blood and plasma. These donations are carefully screened for quality and safety. If you have ever had a severe allergic reaction to immune globulin, you shouldn’t take Asceniv.
You should also avoid taking this medication if you have developed antibodies to immunoglobulin A (IgA) after taking a plasma product following an IgA deficiency. Hypersensitivity reactions can occur, so it is important to get immediate medical care if you think you are having an allergic reaction to Asceniv.
Once you start taking Asceniv, it can significantly reduce how often you become ill. In a clinical study of 59 patients with primary immunodeficiency, no one suffered from any bacterial infections or had to be hospitalized during a 12-month window. In addition, the average participant only missed 1.7 days of school or work.
Cabenuva
Manufacturer website:
https://www.cabenuva.com/Condition:
- Human Immunodeficiency Virus (HIV) Prevention
Cabenuva is a long-acting treatment for human immunodeficiency virus (HIV). Typically, patients are given two injections one month apart for the first two months. Afterward, you will receive subsequent injections every one or two months.
Cabenuva is an injectable treatment you can use to reach undetectable levels of HIV. By taking these regular injections, you may be able to stop taking daily pills.
You can work with your doctor to choose a target date for getting your injection each month. While it is best to get your injection on your target date, the medication can still work as long as you get your injection seven days before or seven days after the right date.
Each injection is made out of rilpivirine and cabotegravir. Together, these two medications can fight off your HIV infection. The medications are slowly released into your body over time, which allows you to maintain the same level of medicine between your injections.
Cimzia
Manufacturer website:
https://www.cimzia.com/Condition:
- Ankylosing Spondylitis
- Crohn’s Disease
- Non-Radiographic Axial Spondyloarthritis
- Plaque Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
Cimzia is a biologic treatment for plaque psoriasis, ankylosing spondylitis, psoriatic arthritis, Crohn’s disease, rheumatoid arthritis (RA), and non-radiographic axial spondyloarthritis. It can help prevent joint damage and improve your overall quality of life. In RA patients, Cimzia was able to improve joint pain in 6 out of 10 patients in just 24 weeks or less.
This injectable treatment is made out of anti-tumor necrosis factor (anti-TNF). TNF is normally used to tell your immune system to fight off infections. When you have excessive TNF, it can cause your immune system to attack your healthy tissues.
Cimzia can help by blocking these extra signals. Once your body stops attacking healthy tissue, you will experience less inflammation.
After your initial dose, you will end up getting another injection at two and four weeks. Following this, the dosage depends on your reaction and what condition you are suffering from. The amount of medication in your injection may also vary because of your body weight.
Crysvita
At the moment, Crysvita is the only medication approved by the Food and Drug Administration for people who have X-linked hypophosphatemia (XLH). In adults and children over the age of 6 months, Crysvita can treat the underlying cause of this progressive disease.
When someone has XLH, their body produces an excessive amount of a protein known as fibroblast growth factor 23 (FGF23). Because they have too much FGF23, their body loses phosphorus. In addition to other symptoms, this can impact the individual’s bone health.
Crysvita can help because it is made out of an antibody that targets the underlying cause of XLH. It can help to boost phosphorus levels in the blood, heal rickets, and improve a child’s growth. In adults, this medication is clinically proven to heal fractures, boost phosphorus levels, heal osteomalacia, and decrease joint stiffness.
Children will receive a dose of Crysvita every two weeks. For adults, this medication is given every four weeks.
Elelyso
If you suffer from Type 1 Gaucher disease, Elelyso may be able to help. This medication is approved for patients who are 4 years old or older. As an enzyme replacement therapy (ERT), it helps to replace enzymes someone’s body isn’t making enough of.
Gaucher disease is a rare, genetic condition that happens in about 1 out of 50,000 to 100,000 people. Among people who have Ashkenazi Jewish heritage, about 1 out of 600 people will have this disease. Gaucher disease affects your lysosomal storage, so your body doesn’t properly make an enzyme known as glucocerebrosidase.
Over the years, this disease can increase the size of your spleen or liver. Elelyso can help by entering Gaucher cells and breaking up the fatty substance inside. This can help to decrease the size of these cells.
You can take Elelyso every other week. After nine months of taking Gaucher, patients in clinical studies saw their spleens and livers decrease in size. The medication also helped to increase their platelets and hemoglobin levels.
Evenity
Many women suffer from osteoporosis after menopause. Unfortunately, this condition can lead to fractures if you don’t take care of it. Through Evenity, you can reduce your risk of fractures and help your body build new bones.
Evenity is unique because it doesn’t just slow down the progression of osteoporosis and bone loss. Over the course of 12 months, it can help your body build new bones.
This medication works in two essential ways. First, it helps to spur your body’s natural ability to create bones. Additionally, it can slow down the progression of your bone loss.
Unlike some medications, you don’t have to take Evenity on a daily basis. Instead, the dose is given via two shots during the same monthly visit. You only have to take Evenity for a single year for it to take effect.
For the medication to work effectively, you also need to take vitamin D and calcium. If you can’t take these supplements consistently, you should talk to your doctor about whether this medication is right for you.
Fasenra
Fasenra is intended for people who have eosinophilic asthma. You might have eosinophilic asthma if you often need to use a rescue inhaler to control your asthma or frequently end up in the emergency room because of asthma attacks. Likewise, needing oral steroids or waking up at night because of asthma symptoms could be an indication of eosinophilic asthma.
Eosinophils are a kind of white blood cell in your immune system. If you have eosinophilic asthma, you have too many eosinophils. This causes excessive inflammation and increased asthma symptoms.
A simple blood test can show if you have elevated levels of eosinophils. If you are a candidate for Fasenra, you can begin taking one injection of this drug every eight weeks. You shouldn’t use this drug if you are allergic to any of the ingredients in Fasenra or benralizumab.
While taking Fasenra, you may experience an allergic reaction or other side effects. If you experience any symptoms while taking this medication, you should talk to your doctor about them right away.
Gammagard (both IV & Inj)
Gammagard is made from human plasma for patients who suffer from primary immunodeficiency. It is available for people who are 2 years old or older. This ready-to-use medication consists of immunoglobulin G (IgG) antibodies, which can help fight off diseases.
When you take this medication, it can temporarily boost the number of antibodies in your body for fighting infections. You can take this as an intravenous (IV) or subcutaneous (SubQ) medication. Over the last 15 years, Gammagard has been the most prescribed Ig in the United States.
As an IV medication, you would take Gammagard every three to four weeks. If you take this medication as a SubQ injection, you would have to take it once a week. As an injection, it may be injected into up to eight spots during each treatment dose.
Severe allergic infections, decreased kidney function, and other side effects can occur. Discuss the risks and benefits of this medication with your doctor before you take it.
Gammagard Liquid (both IV & Inj)
Gammagard Liquid can be given as an intravenous (IV) medicine and an injection. You should tell your doctor about your current medical conditions and if you are pregnant or nursing before you take this medication.
If you decide to take it as an IV medication, you will need to go to an infusion center every three to four weeks. For Gammagard injections, you will need to go to the treatment center every week.
Gammagard S/D (IgA <1 mcg/mL) (both IV & Inj)
Gammagard is made out of immunoglobulin G (IgG) antibodies, which are derived from human plasma. Afterward, this medication is turned into a liquid for patients who have primary immunodeficiency.
You can take this medication as an intravenous (IV) treatment or an injection. Gammagard is given as a weekly injection. If you choose the IV option, you will need to get an infusion every three or four weeks.
Gammaked
If you suffer from primary immunodeficiency, idiopathic thrombocytopenic purpura (ITP), or chronic inflammatory demyelinating polyneuropathy (CIDP), Gammaked could be a good choice for you. This medication is given as an immune globulin (Ig) injection. It can be used to prevent relapse and enhance neuromuscular abilities in CIDP patients.
If you have ITP, Gammaked can help to improve your platelet counts. You may also take it before surgery to prevent excessive bleeding. This medication can also be given to improve primary immunodeficiency in patients who are 2 years old and older.
Gammaked can be given intravenously or subcutaneously. It can’t be given as an injection if you suffer from ITP or CIDP. You can only get Gammaked as an injection if you suffer from primary immunodeficiency. These SubQ injections can be given in up to eight spots at a time on your body, and you will repeat these injections each week.
Givlaari
Givlaari is prescribed as a medication for acute hepatic porphyria (AHP). This disease causes problems with heme production in the liver because of a genetic mutation. Because an enzyme known as aminolevulinic acid synthase 1 (ALAS1) is activated, it can cause toxic substances to build up and cause other symptoms.
Givlaari can treat AHP by reducing the amount of ALAS1 in your liver. This prevents toxic substances from developing and causing the symptoms of AHP.
If your doctor decides this is the right medication for you, you will be given Givlaari once each month. It is typically given as a subcutaneous injection underneath your skin. If you accidentally miss an injection, you should take it as soon as possible.
If you experience any side effects while taking this drug, you should report them to your doctor right away. Other than allergic reactions, the most common side effects were nausea, injection site reactions, rashes, changes in kidney function, fatigue, and changes in liver function.
Ilaris
Manufacturer website:
https://www.ilaris.com/Condition:
- Adult-Onset Still's Disease (AOSD)
- Cryopyrin-Associated Periodic Syndromes (FCAS & MWS)
- Familial Mediterranean Fever (FMF)
- Hyperimmunoglobulin D Syndrome/Mevalonate Kinase Deficiency (HIDS/MKD)
- Systemic Juvenile Idiopathic Arthritis
- Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
If you suffer from an autoinflammatory disease, Ilaris might be able to help. Adults and children over the age of 4 can use this medication for familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS). For FCAS and MWS, you will receive a subcutaneous injection every eight weeks.
Adult and pediatric patients who have tumor necrosis factor receptor associated periodic syndrome (TRAPS), hyperimmunoglobulin D syndrome (HIDS), mevalonate kinase
deficiency (MKD), familial Mediterranean fever (FMF), adult-onset Still’s disease (AOSD), and
systemic juvenile idiopathic arthritis (SJIA) can get this injection every four weeks. If you don’t achieve a clinical response from this dosage schedule, your doctor may increase the size of your dose. The size of your dose can also vary according to your weight.
Side effects, like a runny nose, can happen in up to 10% of patients. Other than a runny nose, some of the most common side effects were bronchitis, influenza, diarrhea, headache, nausea, increased weight, vertigo, musculoskeletal pain, gastroenteritis, and pharyngitis.
Ilumya
If you have moderate to severe plaque psoriasis, you may be able to benefit from taking Ilumya. This medication is given as an injection to help balance your immune system. It can help to decrease the plaques and redness you typically see on your skin.
As a biologic medication, Ilumya is created from natural sources. It is designed to block the IL-23 molecule, which can help improve the symptoms of plaque psoriasis. Unlike some medications, Ilumya targets the right part of the immune system instead of affecting the entire immune system.
You will initially receive two starter doses about four weeks apart. Afterward, you will be given your additional doses every 12 weeks. This works out to about four doses per year after your starter doses.
To help reduce flares, you should also decrease your alcohol intake. A cold compress can also help if you have a flare that causes itching or burning sensations.
Kalbitor
If you have an hereditary angioedema (HAE) attack, Kalbitor can reduce your symptoms over the next four hours. This medication targets plasma kallikrein. By doing this, it can reduce the amount of bradykinin your body makes.
Once Kalbitor reduces the production of bradykinin, it can decrease the HAE attack’s swelling and pain. While it can’t cure HAE, Kalbitor can help alleviate HAE attacks in people who are over the age of 12.
Kalbitor is designed as an on-demand treatment. This means you only take Kalbitor if you need it because of an HAE attack. When you notice the symptoms of an HAE attack, you should call your doctor and get a Kalbitor injection.
If you are pregnant, nursing, or plan on becoming pregnant, you should talk to your doctor before taking Kalbitor. In some people, this medication can cause a severe allergic reaction. You shouldn’t take Kalbitor if you are allergic to it.
Leqvio
Leqvio can help people who want to lower their bad cholesterol (LDL). This medication is typically prescribed for people who are already taking a statin and have a history of heart disease. In addition, you should also adopt a heart-healthy diet.
In clinical studies, people were able to lower their cholesterol by 50% after taking Leqvio and a statin. More importantly, they were able to keep their cholesterol down during the entire dosing interval.
By taking this medication, you can help your body naturally remove bad cholesterol. Initially, you will take one dose followed by a second starter dose three months later. Afterward, your maintenance doses will occur every six months.
Some people have a reaction to their injections. In clinical studies, the most common side effects of this medication were injection site reactions, urinary tract infections, chest colds, leg pain, arm pain, joint pain, diarrhea, and shortness of breath.
Nucala
If you suffer from eosinophilic asthma, you can be given Nucala injections as an add-on medication. This maintenance treatment is designed to be a part of your ongoing treatment plan, so it isn’t intended for acute asthma attacks.
You may have severe asthma if you are frequently using your rescue inhaler, wheezing, or coughing. If you are taking asthma medications and still wake up at night with difficulty breathing, you may need extra help. You can talk to your doctor to see if a diagnosis of eosinophilic asthma is accurate for you.
Eosinophils are white blood cells. When you have too many eosinophils, it can cause extra lung inflammation and more asthma attacks. You can easily see if you have eosinophilic asthma by getting a blood test to check your eosinophil levels.
If you have severe asthma, you will typically receive an injection of Nucala every four weeks. For other conditions, the dosage schedule can vary.
Prolia
Prolia was created for postmenopausal women who have a high risk of developing a fracture. It is especially useful for women who can’t use other osteoporosis medications or who have had an unsuccessful experience with them. In addition, it can also be used by men who are suffering from bone loss.
This medication is a targeted treatment. It can stop bone-removing cells in their tracks, so they can’t hurt your bones. You shouldn’t take this medication if you are pregnant or have low calcium levels.
Prolia is typically given once every six months. If you miss your expected dose, you should take it as soon as possible afterward. Afterward, you should schedule your next dose for six months later.
To take this medication, you need to take vitamin D and calcium supplements. While there is a chance of side effects while taking Prolia, there is also a risk of fractures if you don’t take it. Before your treatment, you should carefully discuss the risks and benefits of Prolia with your doctor.
Revcovi
Manufacturer website:
https://revcovi.com/Condition:
- Adenosine Deaminase Severe Combined Immune Deficiency (ADA-SCID)
Revcovi is the only drug approved by the Food and Drug Administration (FDA) for treating adenosine deaminase severe combined immune deficiency (ADA-SCID). Designed for adult and pediatric patients, this drug is an enzyme replacement therapy (ERT). As an ERT, it can replace the ADA enzyme in people who have ADA-SCID.
ADA-SCID happens because someone is born with a deficiency in ADA. Normally, ADA helps your body get rid of leftover material after your cells divide. Because ADA doesn’t work right in people with ADA-SCID, the leftover material begins to build up.
Before long, this leads to the creation of toxic deoxyadenosine nucleotide (dAXP). This toxic material can remove important immune cells, which means your body can’t fight off infections properly. Revcovi is able to help by replacing ADA, so your body can effectively remove leftover materials from cell division.
You will be given injections of Revcovi twice each week. Your doctor will periodically take blood tests to see if the medication is working for you.
Skyrizi
Manufacturer website:
https://www.skyrizi.com/Condition:
- Crohn’s Disease
- Plaque Psoriasis
- Psoriatic Arthritis
Skyrizi can be taken as an injection for plaque psoriasis, Crohn’s disease, and psoriatic arthritis. For Crohn’s disease, Skyrizi is given as an infusion at zero, four, and eight weeks. Afterward, maintenance doses are given as an injection at week 12 and every 8 weeks after that.
If you have plaque psoriasis or psoriatic arthritis, you will receive your initial injections at zero and four weeks. After that, you will be given your subsequent doses every 12 weeks. If you have psoriatic arthritis, you may be given Skyrizi in conjunction with other non-biologic disease-modifying antirheumatic drugs (DMARDs).
Skyrizi is a biologic medicine that is made out of an interleukin-23 (IL-23) inhibitor. In patients who had psoriatic arthritis, Skyrizi was able to decrease their stiffness, swelling, and joint pain. About three out of four people who had plaque psoriasis were able to enjoy 90% clearer skin after taking Skyrizi injections for four months.
Stelara (Injection)
Manufacturer website:
https://www.stelarainfo.com/Condition:
- Crohn’s Disease
- Plaque Psoriasis
- Psoriatic Arthritis
- Ulcerative Colitis
Stelara can be given to adults who have Crohn’s disease or ulcerative colitis. It can also treat children over the age of six and adults who have psoriasis or psoriatic arthritis.
Stelara works by impacting the way your immune system functions. In clinical trials, it was found to help patients who had problems with previous medications. The majority of patients were able to achieve rapid relief from Crohn’s disease after just one dose of Stelara.
For ulcerative colitis and Crohn’s disease, the first dose of Stelara is an infusion. Eight weeks later, you will be given an injection of Stelara. Afterward, you will receive an injection every eight weeks.
With adult psoriasis patients, the initial doses are at zero weeks and four weeks. Following this, the doses will occur every 12 weeks. Pediatric patients have the same dosage schedule as adults, but the dose size is based on their weight.
Subcutaneous immunoglobulins (SCIg)
Condition:
- Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
- Hepatitis
- Human Immunodeficiency Virus (HIV) Prevention
- Primary Immunodeficiency
Subcutaneous immunoglobulins (SCIg) are given via a slow injection. This injection is called subcutaneous because it is given in the fatty tissue under your skin. Depending on the medication, you will typically get SCIg one to three times per week.
SCIg is used for diverse illnesses, like chronic inflammatory demyelinating polyneuropathy (CIDP), primary immunodeficiency, hepatitis, primary immunodeficiency, and human immunodeficiency virus (HIV). These products are taken by separating plasma from human blood and screening it for quality. Depending on the medication, you may be given your dose via multiple injection sites at the same time.
Normally, SCIg is tolerated fairly well by most patients. Swelling is a common reaction at the injection site. If the needle was placed incorrectly, you may feel itching and burning as well.
You should report any side effects to your doctor or the treatment center right away. Depending on the side effect, your doctor may be able to treat the symptoms or switch the medication you are given.
Tezspire
Tezspire is designed to be an add-on medication for people who have severe asthma, so it isn’t intended to be a rescue medication. By taking Tezspire, you may be able to experience fewer asthma attacks, better lung function, and improved breathing. It can also help you get your asthma symptoms under control.
An estimated 1.3 million people suffer from uncontrolled severe asthma. If you have to use your quick-relief inhaler at least twice a week or need to refill it two or more times a year, you may have severe asthma. In addition, your asthma may be severe if it wakes you up during the night at least twice per month.
When your body interacts with an asthma trigger, your lungs start a chain reaction. Part of this chain reaction is an inflammatory response. Tezspire functions by blocking this chain reaction from causing inflammation and asthma attacks.
Tezspire is intended for adults and children over the age of 12. This medication is given in a healthcare setting once every four weeks. If you end up missing a scheduled injection on accident, you should call your healthcare provider to see when your next dose should be rescheduled.
Thyrogen
Thryogen consists of recombinant human thyroid stimulating hormone (rhTSH). This means you can take this with your normal medication to prevent the symptoms of hypothyroidism when you need a diagnostic test or a similar procedure. It is created to be identical to natural human thyroid-stimulating hormone (TSH).
Basically, Thyrogen uses this protein to increase the levels of TSH in your body. This can help doctors monitor your body for the recurrence of thyroid cancer. It can also help you prepare for RAI ablation.
Patients are typically given this medication as an injection into their buttocks. The injection is given for two days in a row by a healthcare provider. Unlike other medications, you don’t have to risk going into thyroid hormone withdrawal (THW) by stopping your medications.
Whenever you need to have RAI ablation and diagnostic testing done, you can schedule Thryogen injections right away. You should always discuss potential side effects and contraindications with your doctor before taking new medications.
Tremfya
If you suffer from plaque psoriasis or psoriatic arthritis, Tremfya may be able to help. In patients with plaque psoriasis, 7 out of 10 patients achieved 90% clearer skin in just 16 weeks. They also suffered from less stinging, itching, and burning.
Among patients with psoriatic arthritis, at least 5 out of 10 patients had 20% less stiffness, swelling, and joint pain after 24 weeks of treatment. Patients had an easier time performing day-to-day activities, like grooming, eating, gripping, reaching, dressing, and walking.
If you have plaque psoriasis and psoriatic arthritis, you will receive a subcutaneous injection at weeks zero and four. Afterward, you will receive your new injections every eight weeks. If you are receiving Tremfya for psoriatic arthritis, you can use this medication in combination with a traditional disease-modifying antirheumatic drug (DMARD).
Some people may have a reaction to taking this medication. The most common adverse reactions were headaches, upper respiratory infections, injection site reactions, gastroenteritis, diarrhea, bronchitis, and joint stiffness.
Vitamin B12
Condition:
- Alcoholism
- Anemia
- Atrophic Gastritis
- Diet
- Immune System Disorders
- Small Intestine Disorders
Vitamin B12 injections typically consist of cyanocobalamin or hydroxocobalamin. Both of these medications can help to increase your blood levels of B12. If you are deficient in B12 for any reason, your doctor may prescribe B12 injections on a regular basis.
This vitamin is needed by your body for creating red blood cells and DNA. It is also important for your brain function. Because your liver can store extra vitamin B12 for years, it can take a long time before you become deficient.
People may become deficient if they follow a vegan or vegetarian diet. You may also become deficient because of anemia, alcoholism, immune system disorders, diseases that affect your small intestine, and atrophic gastritis
If you are deficient in vitamin B12, your doctor may prescribe these shots every two to three months for the rest of your life. Depending on the underlying cause, you may be given B12 injections in conjunction with other medications as well.
Xolair
Xolair can treat allergic asthma in adults and children who are over the age of 6. It can also treat chronic hives in patients over the age of 12. Additionally, adults who have nasal polyps can use Xolair for symptom relief.
If you suffer from asthma, you will most likely receive your injection every two or four weeks. For nasal polyps, Xolair is also prescribed every two to four weeks. Patients who have chronic hives with an unknown cause will receive their injection every four weeks.
At the moment, Xolair is the only drug approved by the Food and Drug Administration (FDA) to treat allergic asthma. Once patients start taking Xolair, they can enjoy significantly decreased asthma attacks. To date, more than 305,000 patients have used this medication for allergic asthma.
This medication works by focusing on immunoglobulin E (IgE). Because IgE is the underlying reason why people suffer from allergic asthma, this can significantly improve symptoms. Xolair can capture IgE in your body, so it can’t lead to an asthma attack.
Zofran (both IV & Inj)
Manufacturer website:
https://www.novartis.com/us-en/sites/novartis_us/files/zofran_inj_0.pdfCondition:
- Chemotherapy-Related Nausea
- Postoperative Nausea
Zofran is intended for patients who are about to have chemotherapy or surgery. As an infusion or injection, it can decrease vomiting and nausea. You can take this medication before you get anesthesia or up to two hours afterward.
When you are given Zofran for chemotherapy, your infusion provider will typically give it to you 30 minutes before your treatment starts. Then, you will have two follow-up doses at four hours and eight hours later.
If you are over the age of 12, you can receive a dose of Zofran for postoperative nausea. This dose will be administered over the course of 30 seconds to five minutes. For children between the ages of 1 month and 12 years, a smaller dose of Zofran can be given.
Zofran can occasionally cause side effects in patients. If you experience fever, diarrhea, or headaches, you should talk to your infusion provider right away. In addition, you shouldn’t use this product if you have a hypersensitivity to any component of it.
Infusion Treatments
Actemra
Manufacturer website:
https://www.actemra.com/Condition:
- Giant Cell Arteritis
- Polyarticular Juvenile Idiopathic Arthritis
- Rheumatoid Arthritis
- Systemic Juvenile Idiopathic Arthritis
- Systemic Sclerosis With Early Interstitial Lung Disease
Actemra is a type of prescription medicine that is typically given to adults who have moderate to severe rheumatoid arthritis (RA). It is only given after you have already tried at least one other disease modifying antirheumatic drug (DMARD). If the DMARD didn’t work for you, you can talk to your doctor about whether Actemra could be used as an alternative treatment.
This medication is also used for people who have giant cell arteritis (GCA), active polyarticular juvenile idiopathic arthritis (PJIA), active systemic juvenile idiopathic arthritis (SJIA), or systemic sclerosis-associated interstitial lung disease (SSc-ILD). If the patient suffers from PJIA or SJIA, they must be at least 2 years old to take the drug. When used for SSc-ILD, Actemra can help to slow down the progression of decline in your lung function.
Actemra works by changing how your immune system functions. Because of this, you are more likely to get an infection or have a serious infection. You should always tell your medical provider about any infections before you start taking Actemra.
Adakveo
If you suffer from sickle cell disease, you may be prescribed Adakveo. By taking this medication patients can reduce the likelihood of having a pain crisis by 45 percent. To be eligible for this medication, you must be over the age of 16.
This medication works by making certain blood cells and blood vessels less sticky. It essentially attaches to P-selectin, which is known to play a major role in blockages. Once Adakveo attaches to this sticky factor, it can prevent some cells from connecting. As a result, you are less likely to experience pain crises.
Adakveo is given as a 30-minute infusion each month. During the initial month, you will receive an extra infusion after just two weeks. Following the first month, patients will switch to monthly treatments.
If you are taking hydroxyurea or similar treatments, you may still be able to take Adakveo as well. You should talk to your doctor to see if you can take Adakveo in conjunction with other medications.
Aldurazyme
Aldurazyme is designed to treat mucopolysaccharidosis I (MPS I). It can treat adults and children who have the Hurler and Hurler-Scheie forms of the disease. In addition, Aldurazyme can also treat people who have moderate or severe cases of the Scheie form of the disease.
Depending on your medical history and other factors, you may be pretreated with antihistamines, antipyretics, or both. The entire treatment will take about three to four hours to complete. Then, you will repeat your infusion each week.
Antihistamines and antipyretics are given because there is a potential for infusion reactions. If you do have a reaction, you should alert the medical staff right away. They may stop the treatment or give you medication to alleviate your symptoms.
Infusion reactions were found in almost a third of patients in clinical trials. In general, the most common infusion reactions were raised body temperature, rashes, headaches, and flushing.
Aralast NP
Aralast NP can boost the level of Alpha1 protein in your lungs and blood. Normally, the treatment is given once a week to help your body replace this key protein. It takes a doctor or nurse just 15 minutes to give this medication intravenously.
Normally, the body creates Alpha1 protein to protect your lungs. It circulates throughout your bloodstream and prevents inflammation after you inhale irritants or develop an infection. When someone has low or absent levels of this important protein, it can lead to lung damage and emphysema.
Often, an Alpha1 deficiency is genetic. A genetic mutation can make it impossible for your body to develop adequate levels of this protein. If you don’t have enough of this protein, you will likely develop lung damage between the ages of 20 and 50 years old.
Roughly one out of every 3,000 to 5,000 people suffer from Alpha1 protein deficiency. With the right medication, it is possible to manage this disease and prevent lung complications.
Avsola
Manufacturer website:
https://www.avsola.com/Condition:
- Ankylosing Spondylitis
- Crohn’s Disease
- Plaque Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Ulcerative Colitis
Avsola can achieve results similar to Remicade. In fact, it can be used in place of your next scheduled dose. It can be used to treat autoimmune conditions, like rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis, Crohn’s disease, ulcerative colitis, and plaque psoriasis.
During your initial treatment, you will receive Avsola at zero, two, and six weeks. Afterward, you will be given your infusions every eight weeks. If you are getting infusions specifically for ankylosing spondylitis, the subsequent infusions are every six weeks.
For most people, the infusions will take about two hours to complete. If you have an incomplete response to the infusions, you may be given your treatments as often as every four weeks. It is important to remember that more frequent doses can carry a higher infection risk.
This biosimilar works like a biologic, and it is made out of living cells. Because Avsola is biosimilar to Remicade, it has a similar safety profile and effectiveness.
Benlysta
Benlysta was the first Food and Drug Administration (FDA) approved medication for lupus and lupus nephritis. It can be given subcutaneously or intravenously (IV) if you suffer from active lupus nephritis or lupus. The Benlysta IV version is approved for children 5 and up who have lupus.
Once someone is taking this infusion, it can significantly decrease their lupus activity. Many patients notice improvements in the function of their immune system and muscles. It can also help your skin, joints, and mouth.
This biology therapy isn’t a steroid, and you can take it with other lupus medications. It works by focusing on the underlying cause of the disease. Benlysta can reduce your disease activity and flare-ups.
Plus, this medication can decrease your steroid doses by 25 percent. Patients are typically given Benlysta every two weeks for the first three infusions. After that, the one-hour infusions are given every four weeks.
Bivigam
Bivigam is unique because it helps people who have primary humoral immunodeficiency (PI) disorders. Most people fight off diseases using their immune system. When someone’s immune system lacks the right defenses for fighting off diseases, they are said to have a PI disorder.
This medication consists of human immune globulin. When you are given Bivigam, your infusion nurse or physician will decide how fast to give the infusion to you based on your comfort and body weight. During the initial infusion, your response will be closely monitored.
If your body handles the infusion dose well, then the infusion rate will be increased after 10 minutes have passed. Then, the infusion speed can be increased every 20 minutes. You will generally have to receive another infusion every three to four weeks.
Bivigam is made by collecting and processing human plasma. The immune globulin is removed from plasma using a centrifuge. Afterward, it goes through extensive quality and safety controls before it is turned into an infusion.
Cerezyme
As a type of enzyme replacement therapy (ERT), Cerezyme is useful for people who suffer from Gaucher disease type 1. It is intended for people who are over the age of 2 who have developed bone disease, anemia, an enlarged liver, low blood platelet count, or an enlarged spleen from Gaucher disease type 1. Originally released in 1994, it is the only ERT that has a long-term track record of safety and efficacy.
While Cerezyme is generally safe, some patients have developed severe allergic reactions after taking the drug. If you notice symptoms, like chest discomfort, rapid heart rate, flushing, or hives, you should seek immediate medical care.
About 15% of patients develop antibodies and an immune response to Cerezyme during their initial year of therapy. When this happens, the individual has a higher chance of having an allergic reaction. Because of this, your doctor may test you for antibodies to detect this problem as early as possible.
Cinqair
Cinqair can help with uncontrolled asthma attacks and improve your quality of life. It can be used with many other asthma medications, and it is ideal if your other medications aren’t effectively controlling your asthma. When you use Cinqair correctly, it can help to improve your breathing as well as prevent severe asthma attacks.
This medication functions by decreasing blood eosinophils. Eosinophils are a kind of white blood cell that is known for making asthma worse. When you are exposed to asthma triggers, eosinophils are produced and begin to multiply.
Because of the eosinophils, you may develop inflammation in your airways, asthma attacks, and other symptoms of asthma. Up to three out of four people who took Cinqair and reduced these eosinophils didn’t have an asthma attack for an entire year.
You shouldn’t take this drug if you are allergic to reslizumab or have an allergy to any other ingredients in the drug. Your medical provider will decide your dose of Cinqair based on your weight. Infusions are given every four weeks and take about 20 to 50 minutes to complete.
Cinryze
Cinryze is used to treat hereditary angioedema (HAE) in children, which can prevent attacks from happening later in life. Starting as early as the age of 6, children can take this medication to decrease the severity and frequency of HAE attacks.
Released in 2008, Cinryze is known as the first C1 esterase inhibitor (C1-INH). The Food and Drug Administration (FDA) approved this drug for treating children, adults, and teenagers for HAW. Pediatric patients can take this drug to limit the amount of acute treatment they need to take.
Normally, people naturally produce C1-INH protein in their bodies. With HAE, people don’t have enough of this key protein. As a result, the body releases plasma kallikrein and bradykinin.
These proteins can cause your small blood vessels to release fluid in areas of your body. You end up suffering from pain and swelling. With Cinryze, you can take the drug intravenously every three to four days to prevent future attacks.
Dalvance
Manufacturer website:
https://www.dalvance.com/Condition:
- Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
If you suffer from acute bacterial skin and skin structure infections (ABSSSI), Dalvance may be able to help. People often develop ABSSSI following infections with Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes, and Streptococcus anginosus group. To prevent the creation of drug-resistant bacteria, it is important to only take Dalvance after your doctor has proven you are infected by one of these bacteria.
In general, adults will normally take two doses of Dalvance. The second infusion will occur one week after your initial infusion. You will be given one of two different dosages based on whether you have normal renal function or not.
Children can also be given this drug, but they are only given a single dose. Their dosage is determined by whether they are under or over the age of 6. Unlike other treatment options, no PICC line is required, which is significantly more convenient for pediatric and adult patients.
Elaprase
Elaprase is typically given to patients who have Hunter syndrome. In patients 5 years old or older, this prescription medication has been found to boost their walking ability. It was originally approved by the Food and Drug Administration (FDA) in 2006.
This prescription medication is based on an enzyme that is known to break down glycosaminoglycans (GAGs). Since these compounds can cause the symptoms of Hunter syndrome, Elaprase can effectively improve the signs and symptoms of the disease. For instance, it can prevent GAGs from building up in the liver and spleen.
Elaprase is considered an enzyme replacement therapy (ERT). It replaces iduronate-2-sulfate, which is missing in people who have Hunter syndrome. To date, it is the only FDA-approved ERT for this illness.
Your dosage will be determined by your weight. Each week, you will be given another dose of Elaprase. Typically, the infusion will take about three hours to complete.
Entyvio
Entyvio is designed to treat moderately to severely active Ulcerative Colitis or Crohn’s disease. Initially, you will be given an intravenous (IV) infusion for 30 minutes at zero, two, and six weeks. Afterward, you will be given your infusion every eight weeks.
If you have tried taking other medications unsuccessfully before, then Entyvio may be for you. People may also want to try Entyvio if they have been using steroids to handle flare-ups or can’t tolerate other medications.
With a normal immune response, your white blood cells are programmed to go throughout your body to protect you from diseases. If you have Crohn’s disease or Ucerative Colitis, some of these white blood cells are going into your gastrointestinal tract (GI) and causing inflammation. This process is what causes the symptoms of your illness.
When you take Entyvio, you can prevent your body from making too many white blood cells. As a result, Entyvio can control the symptoms of Crohn’s disease and ulcerative colitis.
Evkeeza
Evkeeza can help patients 12 and older with their high cholesterol. This medication is designed to help if you suffer from Homozygous Familial Hypercholesterolemia (HoFH).
In about 1 out of 250,000 people, HoFH occurs and prevents the body from clearing out bad cholesterol. Because of this, your cholesterol may be up to four times higher than normal. Unfortunately, many sufferers aren’t diagnosed until later in life.
HoFH is a serious disease that is inherited from your parents that dramatically limits the body’s ability to remove bad cholesterol (LDL-C), which causes extremely high levels of bad cholesterol to remain in the body. EVKEEZA uses a unique pathway by blocking a specific protein, angiopoietin-like 3 (ANGPTL3), which stops the body from removing bad cholesterol.
You should take Evkeeza with other medications to lower your cholesterol. In addition, you should continue following the heart-healthy or low-fat diet your doctor has prescribed. Because this medication doesn’t affect your liver, you don’t need extra blood tests to monitor your liver health during treatment.
When you get your infusion, the entire process will take about 60 minutes to complete. You will generally take this medication every four weeks. After each appointment, you can schedule your next infusion treatment with your health provider or the infusion center.
Exondys 51
Known as the first treatment for Duchenne muscular dystrophy approved by the Food and Drug Administration (FDA), Exondys 51 is for people who have a confirmed mutation in their dystrophin gene. By taking Exondys 51, you may be able to help your body make a shorter version of the dystrophin protein.
While the infusion typically takes just 35 to 60 minutes to complete, preparation can take a little longer. If you experience any side effects, you may have to temporarily stop the medication or take it at a slower pace. This infusion is typically administered once a week.
When someone’s body doesn’t make dystrophin properly, muscle cells weaken and become damaged. Exondys 51 can alleviate this problem through exon-skipping technology. Basically, Exondys 51 helps your body skip an exon in the dystrophin gene, so you can make a shorter form of the dystrophin protein.
The most common side effects were problems with balance, confusion, and vomiting. If you experience any side effects during the infusion, you should bring them up with your medical provider right away.
Allergic reactions, including wheezing, chest pain, cough, rapid heart rate, and hives have occurred in patients who were treated with EXONDYS 51. Seek immediate medical care if signs and symptoms of allergic reactions occur.
Fabrazyme
As a kind of enzyme replacement therapy (ERT), Fabrazyme is made to replace the enzyme that is missing in Fabry disease. By getting this infusion, you can prevent a fatty substance known as GL-3 from building up in the future. Normally, GL-3 build-up can cause organ damage after it develops in your organs.
In research studies, five months of Fabrazyme treatment helped 69 percent of patients to have nearly no GL-3 inclusions in their kidneys. 72 percent of patients achieved this level in their heart, and 100 percent reached almost no Gl-3 inclusions in their skin
Currently, Fabrazyme can be taken by patients who are 2 years old or older. Your first infusions will always take place at a doctor’s office or an infusion center.
During the infusion, some people may develop side effects. If you have previously had a reaction to other infusions, your doctor may recommend anti-fever or antihistamine medications prior to taking Fabrazyme.
Gammagard
Gammagard is based on human immune globulin. It is designed for people who suffer from primary immunodeficiency (PI). Patients have been successfully using this medication for more than 15 years.
If you are age 2 or older, you could be a candidate for this infusion. This medication can be administered subcutaneously or intravenously depending on your personal needs. Your doctor can help you figure out which method is right for you.
This medication is made from immunoglobulin G (IgG) antibodies. Because of this, the infusion can protect you from getting an infection. Basically, Gammagard uses antibodies from healthy people to replace the antibodies missing in someone who has PI.
As an intravenous (IV) medication, Gammagard is administered every three to four weeks. Because some people experience side effects or severe allergic reactions, it is important to alert your infusion provider to any symptoms you experience during your infusion. If you have immunoglobulin A (IgA) deficiency or previous allergic reactions to blood products or immune globulin, you shouldn’t take this medication.
Gammagard Liquid
Gammagard Liquid is designed for people who have primary immunodeficiency. You can receive this medication subcutaneously or intravenously.
As an intravenous (IV) medication, it is infused into your blood vein. When you take Gammagard Liquid as a subcutaneous medicine, it is injected under your skin into your fatty tissue.
Gammagard S/D (IgA <1 mcg/mL)
Gammagard S/D (IgA <1 mcg/mL) is designed to support your body’s natural immune response to infections. It is made for people who have a weakened immune system because of primary immunodeficiency (PI).
This medication can be given under your skin or directly into your blood vein. Other than PI, it can also be used for idiopathic thrombocytopenia purpura (ITP) or chronic inflammatory demyelinating polyneuropathy (CIDP).
Gammaplex
Gammaplex is intended as replacement therapy for adult and pediatric patients over the age of 2. It is designed for people who have primary humoral immunodeficiency (PI), like X-linked agammaglobulinemia, Wiskott-Aldrich syndrome, common variable immunodeficiency, chronic immune thrombocytopenic purpura (ITP), and congenital agammaglobulinemia. It can also be used by patients who have severe combined immunodeficiencies.
Whether you receive Gammaplex 10% or 5%, you will take Gammaplex every three to four weeks if you have PI. For ITP patients, Gammaplex 10% and 5% are given for two consecutive days. With Gammaplex 5%, the most common side effects were high temperature, headache, nasal congestion, nausea, and sinusitis.
During the infusion, your vital signs will be monitored. If you show any signs of a reaction, the infusion will be slowed or stopped temporarily. Patients with renal insufficiency shouldn’t be volume depleted before they take Gammaplex, and you may have to discontinue taking Gammaplex if it turns out your renal function is declining.
Glassia
Glassia is the first drug approved by the Food and Drug Administration (FDA) for treating emphysema. If your emphysema is caused by severe Alpha1‑antitrypsin (AAT) deficiency, you may be a candidate for this infusion. It is only intended for people who have emphysema caused by AAT deficiency, so it won’t work if your emphysema is due to other problems.
When someone doesn’t have enough functional AAT, it can lead to lung damage later on in life. In most cases, this occurs between the ages of 20 and 50. Unfortunately, around 1 out of 3,000 to 5,000 Americans suffer from AAT deficiency.
At the maximum infusion rate, your infusion will take about 15 minutes to complete. Because it is a chronic maintenance therapy, Glassia is given on a weekly basis to boost the levels of AAT in your lungs and bloodstream.
Glassia can sometimes cause severe allergic reactions in patients. If this occurs, you should notify your infusion provider right away.
Hydration
Condition:
- Dehydration
Hydration therapy might be required for many different conditions. During this infusion, an intravenous (IV) line is inserted into your arm. Then, fluids and electrolytes are delivered directly into your bloodstream.
The liquid contains potassium, sulfate, calcium, B vitamins, magnesium, and other electrolytes. Your hydration infusion can vary based on your current medical conditions, age, medical history, and how dehydrated you are.
If you are dehydrated, hydration infusions can help you recover faster. Instead of having to go through your entire digestive system first, the fluids and electrolytes can immediately get absorbed in your bloodstream. An infusion can also be easily customized to meet your needs.
When you’re severely dehydrated, drinking a lot of fluids and electrolytes can overload your digestive system. In these cases, it may be easier to get an IV instead of trying to replenish your body through drinking fluids. In addition to being more effective, hydration infusions also take less time to do.
HyQvia
HyQvia is intended for adults who suffer from primary immunodeficiency. It is made out of recombinant human hyaluronidase and immune globulin (Ig). This medication is proven to help your body fight off infections. HYQVIA is a liquid medicine that is given under the skin (subcutaneously) to treat primary immunodeficiency (PI) in adults.
Normally, this infusion is given every three to four weeks. Because it uses a ramp-up schedule, you will have more infusions initially as your body gets used to the medication. Most people have infusions at one, two, four, and seven weeks before switching to a monthly dose.
Hyaluronidase is the reason why you can get infusions on a monthly basis. It is found naturally in your body and helps to open up your skin. This allows more Ig to reach your bloodstream, which means you can have just one infusion a month.
After initially getting hyaluronidase during your treatment, the second part of your infusion will consist of Ig. Thanks to Ig, your body will get a bunch of antibodies for fighting off potential infections.
Inflectra
Manufacturer website:
https://inflectra.pfizerpro.com/Condition:
- Adult and Pediatric Crohn’s Disease
- Adult and Pediatric Ulcerative Colitis
- Ankylosing Spondylitis
- Plaque Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
If you have taken Remicade, you can generally take Inflextra instead. This medication is intended for adult and pediatric patients who have Crohn’s disease and Ulcerative Colitis. You may also be able to take it if you suffer from psoriatic arthritis, plaque psoriasis, ankylosing spondylitis, or rheumatoid arthritis.
As a biosimilar to Remicade, Inflectra is used for similar purposes. It is also dosed in a similar way. This means patients with Crohn’s disease start by getting an infusion at zero, two, and six weeks.
After the initial doses, you will be given Inflectra every eight weeks. If your body no longer seems to be responding, the amount of Inflectra may be increased during your infusions.
Rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, and ulcerative colitis have similar dosing schedules, but the amount you receive during each treatment may be different. For ankylosing spondylitis, the maintenance phase involves infusions every six weeks instead of eight weeks.
Intravenous Antibiotics
Condition:
- Infections
- Sepsis
Intravenous (IV) antibiotics are available in many different forms. Once you are given IV antibiotics, they can immediately enter your bloodstream. Because they don’t have to be absorbed by your gut, more of the medication can be absorbed than oral antibiotics.
In addition, IV antibiotics can also be absorbed faster than oral antibiotics. Because of this, IV antibiotics are often used for sepsis and serious infections.
Other than sepsis, IV antibiotics can be used to treat meningitis, cellulitis, septic arthritis, abscess infection, ruptured appendix, endocarditis, and osteomyelitis. The type of medication can vary based on the cause of your infection.
IV antibiotics are reserved for deep-seated infections and severe infections. Depending on your situation, you may be hospitalized. You may also be allowed to receive your treatment at an infusion center before returning home at night. Before your treatment, talk to your doctor about how long it will take and what you should expect.
IV Antifungals
Condition:
- Fungal Infections
Intravenous (IV) antifungals are given for certain kinds of fungal infections. For example, echinocandin anidulafungin is only available intravenously. If you need it to treat Candida spp. infections, like candidemia or esophageal candidiasis, your treatment will be administered through an IV.
There are also three antifungal medications you can take intravenously or orally. These are fluconazole, voriconazole, and flucytosine.
While echinocandin anidulafungin has to be taken by IV, the other three antifungals don’t. They are generally given by IV when you have a severe infection or a deep-seated infection your doctor thinks will only respond to IV infusions. Because IV infusions bypass your gut, more of the medication is absorbed by your body, and the medication can reach a higher concentration in your bloodstream.
The amount of time your treatment takes and the number of infusions you need can vary based on the medication and the cause of your fungal infection. All infusions carry some potential side effects, so you should talk to your doctor about what to expect before you begin your IV antifungal treatment.
IV Antivirals
Condition:
- Viral Infections
Antiviral medications are designed to help your body fight off viruses. They can shorten how long you are sick as well as alleviate some of your symptoms. While you can often recover from viruses without antivirals, you may need this medication if you have a life-threatening or chronic illness.
Antiviral medication is generally taken intravenously or orally. Intravenous (IV) antivirals are absorbed directly by your bloodstream, which allows the medication to reach a higher concentration. In addition, more medication can be absorbed through this method.
The type of IV antiviral you receive will depend on which virus you are infected by. In addition, the time it takes to complete your infusion and the frequency of your infusions can vary. If you have questions about how long you will need infusions or what side effects to expect, you can talk to your doctor or infusion provider before your infusion treatment begins.
IV Steroids
Condition:
Intravenous (IV) steroids can be prescribed for many medical conditions, and there are a number of oral steroids that can also be delivered through an IV. Often, people use corticosteroids for lupus, rheumatoid arthritis, asthma, multiple sclerosis, and fibromyalgia. In a low dose, people can use IV steroids to relieve stiffness and pain in conditions like rheumatoid arthritis.
Depending on the type of IV steroid, the infusion can take a varying amount of time to complete. Many treatments take around two to four hours. Because the medication is delivered directly to the bloodstream, the effects tend to occur fairly quickly.
Like oral steroids, IV steroids can carry potential side effects. If you experience any side effects during your treatment, it is important to tell your doctor or infusion provider right away because there are medications and techniques available for mitigating side effects. The infusion provider may also decide to halt or slow down the infusion to alleviate some of your symptoms.
IVIG (e.g. Gamunex-C)
Condition:
- Autoimmune diseases
- Chronic Inflammatory Demyelinating Polyneuropathy
- Chronic Lymphocytic Lymphoma
- Immune Thrombocytopenia (ITP)
- Kawasaki Disease
- Multifocal Motor Neuropathy
Intravenous immunoglobulin (IVIG) is used by patients who have an antibody deficiency. After healthy donors provide plasma, a pool of antibodies is transformed into IVIG. Also known as immunoglobulins, these antibodies are a normal part of healthy immune systems and are important for fighting off infections.
Plasma-based immunoglobulin products have been used since 1952 for primary immune deficiency. Today, IVIG products are purified and normally have more than 95% IgG. While immunoglobulin was originally injected into patients, it can now be given as an infusion.
Like many medications, IVIG can cause some side effects. This is especially true if you are trying IVIG for the first time, or you haven’t used IVIG for at least eight weeks.
IVIG is typically prescribed to make your immune system stronger. It can also be used to boost platelet levels if you have chronic immune thrombocytopenia (ITP). Additionally, IVIG can help people who have chronic inflammatory demyelinating polyneuropathy (CIDP).
Ixifi
Manufacturer website:
https://www.pfizer.com/products/product-detail/ixifi_for_injection_for_intravenous_useCondition:
- Ankylosing Spondylitis
- Crohn’s Disease
- Pediatric Crohn’s Disease
- Plaque Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Ulcerative Colitis
Ixifi is made for people who have rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis, Crohn’s disease, or ulcerative colitis. It is considered a tumor necrosis factor (TNF) blocker, which can help conditions that involve immune issues.
A TNF blocker works by tamping down the immune system. The medication blocks TNF from functioning normally. Because TNF can cause inflammation in immune-system diseases, a TNF blocker can prevent some of the symptoms of rheumatoid arthritis, Crohn’s disease, and similar illnesses.
While the dosage amount can vary from one disease to another, the dosing schedule is generally the same. Initially, you will receive your infusion at zero, two, and six weeks. Afterward, you will receive your infusions every eight weeks if you have any illness other than rheumatoid arthritis and ankylosing spondylitis.
If you suffer from ankylosing spondylitis, your maintenance doses will occur every six weeks. Meanwhile, maintenance doses will occur every four weeks for people who have rheumatoid arthritis.
Kanuma
If you suffer from lysosomal acid lipase deficiency (LALD), Kanuma may be able to help you manage your disease. This genetic condition is a progressive disease that eventually leads to multiorgan damage. It can affect infant, pediatric, and adult patients.
Kanuma infusions are made out of hydrolytic lysosomal cholesteryl ester and triacylglycerol-specific enzymes. Pediatric and adult patients will get their infusion once every other week.
You can expect the infusion to take two hours to complete. Preparing for the infusion and cleaning up afterward can take longer. To make the time go faster, you can bring along a book, movie, or mobile device to help you pass the time.
If you have a hypersensitivity reaction to the infusion, you should tell the infusion provider. People who have an allergy to eggs and egg products should carefully discuss the risks and benefits of this treatment with their doctor before they receive their first infusion.
In pediatric and adult patients treated with KANUMA, the most common side effects are headache, fever, sore throat, swelling of the nose and throat, weakness, constipation, and nausea.
Krystexxa
Krystexxa is intended for people who suffer from chronic gout. If you experience two or more flare-ups each year, it could be a sign your current medication isn’t decreasing your uric acid levels enough. Because of this, your body may be suffering from the damage of uncontrolled gout.
For more than 10 years, Krystexxa has helped patients manage chronic gout. Currently, it is the only medication approved by the Food and Drug Administration (FDA) for treating gout that isn’t controlled by other medications. In many cases, patients can take a single intravenous (IV) treatment every other week for six months to get their gout under control.
After a single treatment, Krystexxa can start lowering your uric acid levels. In healthy adults, the kidneys remove uric acid from the blood. When someone has out-of-control gout, their body needs extra help getting rid of uric acid.
Krystexxa gives your body an enzyme it needs for transforming uric acid into allantoin. Once this process occurs, uric acid can leave your body through your urine. As a result, you can manage your gout and have fewer flares.
LEQEMBI
The U.S. Food and Drug Administration (FDA) has approved the supplemental Biologics License Application (sBLA) supporting the traditional approval of LEQEMBI® (lecanemab-irmb), making LEQEMBI the first and only approved treatment shown to reduce the rate of disease progression and to slow cognitive and functional decline in adults with Alzheimer's disease (AD). LEQEMBI is for people in the early stages of Alzheimer’s disease, which are known as:
- Mild cognitive impairment (MCI) due to Alzheimer’s disease. This is when symptoms like forgetfulness and confusion are very mild and may not get in the way of daily life.
- Mild Alzheimer’s dementia This is when symptoms like trouble keeping track of bills and difficulty with familiar tasks start to get in the way of daily life
Lumizyme
Pompe disease causes an acid α‑glucosidase (GAA) deficiency. This rare disorder can disable the skeletal and heart muscles. It makes it impossible for your body to make enough protein to break down sugar.
Because your body can’t break down the glycogen molecules, they build up in your body. Before long, this causes damage to your organs and muscles. It can impact your liver, heart, and other muscles.
Lumizyme is an enzyme replacement therapy (ERT) for Pompe disease. If you are taking it via infusion instead of as an injection, you will be given a dose every two weeks. Because there is a risk of a hypersensitivity reaction or anaphylaxis, it is important to report any side effects you experience to your doctor or the infusion provider.
If you suffer from cardiovascular problems, you should carefully discuss the risks and benefits of this drug with your doctor before you take it. Lumizyme can cause cardiorespiratory failure in patients who already have decreased cardiovascular or respiratory function.
Mepsevii
Mepsevii is typically prescribed for patients who are diagnosed with Mucopolysaccharidosis VII (MPS VII). Also known as Sly syndrome, this illness is an autosomal recessive lysosomal storage disease. It happens because the body can’t break down sugar molecules known as glycosaminoglycans (GAGs).
After GAGs accumulate in the body, they can end up causing organ and tissue damage. Often, symptoms begin appearing early on in childhood.
When you get your infusion, you can expect the process to take at least four hours. Normally, you will be given an infusion every two weeks. The infusion rate is slower during the first hour, but it is increased as your body adjusts to the infusion process.
To make the infusion more comfortable, many patients are given a nonsedating antihistamine or an antipyretic 30 minutes to an hour before the infusion begins. You can talk to your doctor about what to expect and how to prepare for your treatment.
Myozyme
Manufacturer website:
https://www.ema.europa.eu/en/medicines/human/EPAR/myozymeCondition:
- Pompe Disease
Myozyme is considered a kind of enzyme replacement therapy (ERT). It is generally used for people who suffer from Pompe disease. As an infusion, this medication contains an ingredient known as alglucosidase alfa.
Pompe disease is famous for being a rare inherited disorder. It impacts your body's production of alpha-glucosidase. Without enough of this enzyme, your body can’t break down sugar into glucose.
Over time, glycogen can build up in the diaphragm, heart, and other muscles. Without treatment, you might develop breathing problems, an enlarged heart, and muscle weakness. In clinical studies, Myozyme helped patients avoid going on a ventilator and allowed them to live longer than the control group.
After your doctor prescribes Myozyme, you will receive an infusion every two weeks. Once you get your infusion, Myozyme will replace the enzymes your body isn’t making. Thanks to the added enzymes, your body will be able to break down glycogen into glucose.
Naglazyme
If you suffer from mucopolysaccharidosis VI (MPS VI), Naglazyme may be able to help your symptoms. Also called Maroteaux-Lamy syndrome, this disease is inherited and can lead to valvular symptoms, impaired vision, spinal cord compression, carpal tunnel syndrome, recurrent sinusitis, and other symptoms. Thankfully, Naglazyme can help you manage your illness.
As the first enzyme replacement therapy (ERT) for MPS VI, Naglazyme helps to replace the enzyme your body needs to process glycosaminoglycan (GAG). In clinical studies, taking Naglazyme was shown to help patients improve their endurance.
If MPS VI isn’t treated, it can cause difficulty breathing, decreased endurance, and other physical problems. Naglazyme helps by giving you the enzyme your body isn’t making. By doing this, the infusion can help you decrease the buildup of GAGs.
You can expect the Naglazyme infusion to take about four hours to complete. Because MPS VI is a lifetime disorder, you will need to continue your treatments for the rest of your life.
Nulojix
Manufacturer website:
https://www.nulojixhcp.bmscustomerconnect.com/Condition:
- Organ Rejection Prevention
Anti-rejection medicines are an integral part of your post-transplant treatment. With Nulojix, you can prevent your body from rejecting an organ transplant. This intravenous (IV) infusion can be used in combination with corticosteroids and other medications.
Nulojix is intended for people who are 18 years old or older. It isn’t designed for anyone who has previously been exposed to the Epstein-Barr virus. In addition, you should talk to your doctor if you are currently pregnant or breastfeeding.
Transplant rejection occurs following organ transplants because your immune system recognizes the new organ is foreign to your body. Nulojix, corticosteroids, and other medications can be used to suppress your immune system and prevent organ rejection.
Like many medications, Nulojix carries some potential risks. Your doctor will give you blood and urine tests to see if it is negatively affecting your body. In general, you can expect each infusion to take about 30 minutes to complete.
Ocrevus (Loading Dose & Maintenance Dose)
If you suffer from primary progressive or relapsing multiple sclerosis (MS), Ocrevus may be able to help. This treatment has proven to be effective at decreasing disability progression and reducing the incidence of relapses. It can also improve brain lesions.
During your initial year, the first treatment is divided into two doses. Then, you will have a follow-up treatment six months later. Afterward, you will only have two treatments per year.
MS happens because your immune system begins attacking myelin, which is a material that surrounds nerves in your brain. B cells are important for MS development because they are responsible for activating your immune system. Currently, scientists believe Ocrevus works by impacting these B cells.
You should plan on spending about four to six hours at the treatment center. The infusion takes just two hours to complete, but additional preparations can cause the entire procedure to take longer. Following your treatment, you should watch for infusion reactions for up to 24 hours afterward.
Octagam
Manufacturer website:
https://octagam-10.pfizerpro.com/Condition:
- Chronic Immune Thrombocytopenia (ITP)
- Dermatomyositis (DM)
Octagam is the first IVIg treatment approved by the Food and Drug Administration (FDA) for treating dermatomyositis (DM). It has also been approved for treating chronic immune thrombocytopenia (cITP). Octagam is made out of human immunoglobulin (Ig), which means it can help raise blood platelet counts in people who suffer from thrombocytopenia.
For DM, you will generally receive your infusions over the course of two to five consecutive days. Then, this infusion schedule will be repeated every four weeks. It will typically take around five hours to complete your infusion.
With chronic ITP, you will be given the same infusion dose size. The main difference is that it will be divided over two consecutive days.
Octagam can occasionally cause adverse reactions. You should tell your infusion provider if you have a hypersensitivity reaction or any other symptoms. In clinical trials, the most common adverse reactions were headaches, high temperature, and increased heart rate.
Onpattro
Onpattro is approved for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis). It can also improve hATTR-related polyneuropathy.
hATTR amyloidosis affects around 50,000 people globally. It typically runs in families, so a child has a 50% chance of developing this disease if one of their parents has it. Because this rare condition damages the nerves, it can cause a diverse range of symptoms, like diarrhea, shortness of breath, heart palpitations, difficulty walking, burning pain, sexual dysfunction, nausea, and weakness.
Onpattro can reduce the amount of TTR protein produced within the liver. Normally, hATTR amyloidosis involves a genetic variant in the TTR gene, which causes TTR protein to make amyloid deposits. By reducing TTR protein, Onpattro can decrease amyloid deposits and symptoms of hAATR amyloidosis.
About an hour before you take Onpattro, your infusion provider will give you medications to prevent infusion-related reactions from happening. Once your infusion begins, it should take about 80 minutes to complete.
Orbactiv
If you are dealing with a gram-positive bacterial infection, you may be prescribed Orbactiv. This medication is given as a single-dose alternative to taking multiple doses of vancomycin. Before you are given this treatment, your doctor will determine if you are suffering from acute bacterial skin and skin structure infections (ABSSSI).
Orbactiv is the first single-dose option for ABSSSI. Unlike some medications, you won’t need a dosing adjustment if you have renal impairment or hepatic impairment. You will also take the same dosage, regardless of your gender, weight, age, or race.
Your infusion will take about three hours to complete. Preparatory work and cleanup may take a little longer. Once your infusion is done, you shouldn’t need to take any more doses in the future.
Orbactiv is considered a lipoglycopeptide antibacterial drug. To avoid creating drug-resistant bacteria, it is important to only take Orbactiv for infections caused or suspected to be caused by ABSSSI bacteria.
Orencia
Manufacturer website:
https://www.orencia.com/Condition:
- Polyarticular Juvenile Idiopathic Arthritis
- Psoriatic Arthritis
- Rheumatoid Arthritis
Orencia is intended for people who suffer from mild to moderate rheumatoid arthritis (RA). By taking Orencia, you may be able to prevent RA from causing additional damage to your joints and bones. In addition, taking this drug may make it easier to carry out your day-to-day activities.
Talk to your doctor about the other RA medications you are on before you take Orencia. In many cases, you can continue taking other RA drugs while you are on Orencia. Orencia can also be taken if you suffer from psoriatic arthritis or polyarticular juvenile idiopathic arthritis.
When you have RA, your immune system mistakenly believes your joints are under attack. Because of this, the immune system will send signals to launch a counterattack. Orencia works by disrupting these signals.
A typical dose of Orencia takes 30 minutes to complete. The amount of time you’ll spend at the infusion center will be longer because the infusion has to be prepared. Afterward, you will return every month for another infusion.
Privigen
Privigen may be prescribed as a treatment for chronic immune thrombocytopenic purpura (ITP), primary immunodeficiency, or chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). This intravenous immunoglobulin G (IVIg) therapy is made out of antibodies. These essential antibodies can help your body fight off diseases.
When you suffer from PI, your body can’t fight off germs properly. Infections are common because your immune system isn’t working right. Privigen works by raising your IgG levels, so your body can fight off recurring infections and other complications.
Your infusion will take place at an infusion center or hospital. Once the intravenous (IV) treatment begins, it will take about two hours to complete. For PI, you will receive your infusion treatments every three to four weeks.
Immunoglobulin products, like Privigen, carry blood-clotting risks. Kidney issues and kidney failure can happen in people who are predisposed to these problems. If you are at risk for blood-clotting issues or kidney disorders, talk to your doctors about the risks and benefits of taking Privigen before you start the treatment process.
Prolastin-C
If you are struggling to live with alpha1-antitrypsin deficiency, Prolastin-C may be able to help. Alpha1-antitrypsin deficiency is also known as genetic chronic obstructive pulmonary disease (COPD) because it can be passed down through your family. When someone suffers from this illness, their body is unable to make a protein that protects the lungs from infections.
About 100,000 people suffer from this illness, but the majority of sufferers don’t realize they have it. If you have this disease, you may develop wheezing, shortness of breath, chronic cough, and low exercise tolerance.
Prolastin-C can help because it is a concentrated version of protein alpha1 antitrypsin, so it can raise your blood levels quickly. It is made out of screened human plasma.
Because there is no cure for alpha1-antitrypsin deficiency, you will have to receive this infusion every week for the rest of your life. At the recommended infusion rate, each infusion will take about 15 minutes to complete.
Radicava
When someone has amyotrophic lateral sclerosis (ALS), it negatively impacts their neurons. Unfortunately, these neurons are responsible for voluntary muscle movements. Initially, you may notice muscle cramps, difficulty chewing, slurred speech, muscle twitches, and similar symptoms.
Radicava is an important treatment for ALS because it can slow the physical progression of your disease by 33%. During research studies, the most common side effects of treatment were bruising, problems with walking, headaches, and fatigue.
As an intravenous (IV) medication, Radicava starts with an initial round of infusions before switching to a different treatment schedule for subsequent treatments. Initially, you will get infusions for 14 consecutive days before having a 14-day break. Afterward, you will have infusions on 10 out of 14 days followed by a 14-day break.
While a full dose takes just 60 minutes to administer, your entire infusion appointment will take a bit longer to complete. On infusion days, you don’t have restrictions on what you can eat or drink. You just have to show up in comfortable clothes.
Remicade
Manufacturer website:
https://www.remicadehcp.com/Condition:
- Adult and Pediatric Crohn’s Disease
- Adult and Pediatric Ulcerative Colitis
- Ankylosing Spondylitis
- Plaque Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
Remicade has been approved for use in the United States since 1998. Throughout the world, more than 2.8 million patients have received this drug. It can treat Crohn’s disease, rheumatoid arthritis (RA), ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and plaque arthritis.
For pediatric and adult Crohn’s disease patients, this medication is given at zero, two, and six weeks. Afterward, infusions are given every eight weeks. If you have adult ulcerative colitis, pediatric ulcerative colitis, psoriatic arthritis, plaque arthritis, or RA, you will use the same treatment schedule.
Ankylosing Spondylitis patients will receive their initial infusions at zero, two, and six weeks. Following this, future doses are given every six weeks.
No matter what you are being treated for, Remicade infusions will take about two hours to complete. You shouldn’t take this drug if you are suffering from moderate to severe heart failure or have a sensitivity to any of Remicade’s ingredients.
Renflexis
Manufacturer website:
https://www.renflexis.com/Condition:
- Adult and Pediatric Crohn’s Disease
- Adult and Pediatric Ulcerative Colitis
- Ankylosing Spondylitis
- Plaque Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
Renflexis is used to treat Crohn’s disease and ulcerative colitis in adults and children. It can also be used for people who have psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, and rheumatoid arthritis. It is a biosimilar to Remicade, which means it can be used the same way as Remicade is.
When you suffer from an autoimmune disease, your immune system may produce too much tumor necrosis factor-alpha (TNF-alpha). If this happens, you can end up developing inflammation and symptoms of autoimmune disorders.
Taking Renflexis can block TNF-alpha from causing inflammation. As a result, you can experience fewer or less severe symptoms of your illness.
Renflexis is typically given as an intravenous (IV) infusion over the course of about two hours. Initially, you will be given three doses of Renflexis over six weeks. After this initial treatment, you will be given Renflexis every six to eight weeks.
If you are suffering from rheumatoid arthritis, you may take Renflexis every four weeks. People who have already taken starting doses of Remicade might not need to take starting doses of Renflexis.
Riabni
Manufacturer website:
https://www.riabni.com/Condition:
- Chronic Lymphocytic Leukemia (CLL)
- Granulomatosis With Polyangiitis (GPA) (Wegener’s Granulomatosis)
- Microscopic Polyangiitis (MPA)
- Non-Hodgkin's Lymphoma (NHL)
- Rheumatoid Arthritis
Riabni is known as a biosimilar of Rituximab. This means it can treat the same conditions using the same dosing as Rituximab. In addition, it has a similar safety and efficacy profile.
While Riabni is frequently used for people who have rheumatoid arthritis (RA), you may also receive this medication if you have non-hodgkin's lymphoma (NHL), chronic lymphocytic leukemia (CLL), granulomatosis with polyangiitis (GPA), or microscopic polyangiitis (MPA). Because severe infusion-related reactions can occur, you should only receive your intravenous (IV) treatment under medical supervision. You should talk to your doctor if you have hepatitis B because Riabni can sometimes reactivite the virus.
For CLL, you will receive an infusion every 28 days. RA patients will receive two doses, spaced two weeks apart. Afterward, they will wait about 24 weeks before having another round of infusions.
With GPA and MPA, patients receive weekly doses for four weeks. Then, your next dose will be two weeks later. After this, you will wait six months until you have another infusion.
Rituxan
Manufacturer website:
https://www.rituxan.com/Condition:
- Chronic Lymphocytic Leukemia (CLL)
- Granulomatosis With Polyangiitis (GPA) (Wegener’s Granulomatosis)
- Microscopic Polyangiitis (MPA)
- Non-Hodgkin's Lymphoma (NHL)
- Pemphigus Vulgaris (PV)
- Rheumatoid Arthritis
Rituxan is a medication you can take for a number of different conditions. Adults with moderate to severe rheumatoid arthritis (RA) can take it when a tumor necrosis factor (TNF) antagonist hasn’t been effective. Meanwhile, adults who have non-Hodgkin’s lymphoma (NHL) or chronic lymphocytic leukemia (CLL) can take it by itself or in conjunction with other chemotherapy medicines.
This medication can be used if you are age 2 or older and suffer from microscopic polyangiitis (MPA). It is also used in adults who have granulomatosis with polyangiitis (GPA). The dosage and infusion schedule are based on the disease you are trying to treat.
Rituxan is made of a cytolytic antibody. For RA, you will space two doses, two weeks apart. Then, you generally wait 24 weeks before repeating those doses.
For GPA and MPA, you would get your infusion each week for four weeks. Once your disease is under control, your follow-up infusion will be two infusions, two weeks apart. Afterward, you will repeat the follow-up schedule six months later.
Ruxience
Manufacturer website:
https://www.ruxience.com/Condition:
- Chronic Lymphocytic Lymphoma
- Granulomatosis With Polyangiitis (GPA) (Wegener’s Granulomatosis)
- Microscopic Polyangiitis (MPA)
- Non-Hodgkin's Lymphoma (NHL)
- Rheumatoid Arthritis
Ruxience is designed for people who suffer from non-Hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), rheumatoid arthritis (RA), granulomatosis with polyangiitis (GPA), and microscopic polyangiitis (MPA). Because it is a biosimilar to Rituxan, it can be used to treat the same conditions. A biosimilar is essentially a drug the Food and Drug Administration (FDA) says has the same safety and efficacy profile as another medication.
Ruxience is given as an intravenous (IV) infusion. Because people sometimes experience fever, chills, or other side effects, your doctor may want to give you other medications beforehand to prevent these symptoms. You will also receive blood tests on a regular basis to spot potential side effects.
You will most likely be given Ruxience on the same schedule as Rituxan. If you have an infusion-related reaction, it will typically occur within the first 24 hours. You should tell your infusion provider or doctor right away if you think you are having an infusion-related reaction.
Saphnelo
If you suffer from lupus, Saphenlo may be able to help. Lupus affects many different parts of your body, and Saphnelo can work in these areas. In addition, this drug is effective with both parts of your immune system.
Systemic lupus erythematosus (SLE) is an autoimmune disorder, which is a disorder where your body’s immune system attacks your organs and tissues. Because different areas can be attacked, lupus sufferers can experience a variety of different symptoms.
When you are born, your body’s immune system was made with an innate defense system as well as abilities you developed over time. With lupus, both aspects of your immune system stop working properly. Higher levels of type 1 interferon (IFN-1) can cause your immune cells to create inflammation as they track your organs.
Taking Saphnelo can help you reduce the amount of steroids you use, flare-ups, and your disease activity. It takes about 30 minutes to complete a full dose of Saphnelo. After you take your first appointment, you will receive follow-up infusions every four weeks.
Simponi ARIA
Manufacturer website:
https://www.simponiaria.com/Condition:
- Adult and Pediatric Psoriatic Arthritis
- Ankylosing Spondylitis
- Polyarticular Juvenile Idiopathic Arthritis
- Rheumatoid Arthritis
Simponi Aria can be used to treat rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis, and polyarticular juvenile idiopathic arthritis (pJIA). While it is used for adults who have RA and ankylosing spondylitis, Simponi Aria can treat anyone over the age of 2 if they have psoriatic arthritis or pJIA.
This biologic treatment is given as an intravenous (IV) infusion. Each infusion takes about 30 minutes to complete. After your initial infusion, you will get a follow-up infusion four weeks later.
Following your initial two infusions, your future infusions will be given every eight weeks. This means you may only need six infusions in a year.
Because Simponi Aria can reduce your body’s ability to fight off infections, you are more likely to experience serious bacterial, fungal, and viral infections. Other serious side effects and allergic reactions may also happen. It is important to talk about any side effects you experience with your doctor or infusion provider.
Skyrizi
Manufacturer website:
https://www.skyrizi.com/Condition:
- Crohn’s Disease
- Plaque Psoriasis
- Psoriatic Arthritis
Skyrizi is available by prescription for people who have psoriatic arthritis, Crohn’s disease, or plaque psoriasis. It is considered an interleukin-23 (IL-23) inhibitor. Because of this, it can change the body’s inflammatory response in autoimmune conditions.
This prescription drug works by attaching to a protein known for causing inflammation. Once it attaches to this protein, Skyrizi is able to reduce the amount of inflammation in your body.
For Crohn’s disease, adult patients should be given an intravenous (IV) infusion for at least an hour. During the induction phase, you will receive an infusion at weeks zero, four, and eight. Then, you will receive a subcutaneous injection at week 12 and every 8 weeks following that.
Like many infusions, it is possible to experience a hypersensitivity reaction. Skyrizi also makes you more susceptible to serious infections, so you shouldn’t take it if you are currently suffering from a clinically active infection.
Soliris
Manufacturer website:
https://solirisgmg.com/Condition:
- Atypical Hemolytic Uremic Syndrome (aHUS)
- Generalized Myasthenia Gravis (gMG)
- Neuromyelitis Optica Spectrum Disorder (NMOSD)
- Paroxysmal Nocturnal Hemoglobinuria (PNH)
Soliris is approved to treat neuromyelitis optica spectrum disorder (NMOSD), generalized myasthenia gravis (gMG), atypical hemolytic uremic syndrome (aHUS), and paroxysmal nocturnal hemoglobinuria (PNH). This medication can prevent certain proteins from becoming activated, which can help with several rare diseases.
Soliris impacts the way your immune system functions. Because of this, it can reduce your body’s ability to counteract infections. Since this increases the odds of developing a serious infection, you must get your meningococcal vaccines at least two weeks before you take your initial dose of Soliris.
While the infusion takes just 35 minutes to complete, you will need to remain at the infusion center for post-infusion monitoring. You will receive an infusion every week for the first five weeks. Afterward, you will receive an infusion every two weeks.
Soliris can sometimes cause major side effects. If you notice problems breathing, chest pain, or other symptoms, you should tell the nurse or infusion provider right away.
Solu-Medrol
Manufacturer website:
https://www.pfizermedicalinformation.com/en-us/solu-medrol/dosage-adminCondition:
- Allergic Reactions
- Dermatologic Conditions
- Endocrine Disorders
- Gastrointestinal Diseases
- Hematologic Disorders
- Multiple Sclerosis (MS)
- Neoplastic Diseases
- Ophthalmic Diseases
- Renal Diseases
- Respiratory Diseases
- Rheumatic Disorders
Solu-Medrol is a corticosteroid, which means it is typically used to change how the immune system works. Because of this effect, it can improve redness, swelling, and itching. Many people also take it for alleviating allergic reactions.
If you suffer from mycosis fungoides or other dermatologic diseases, you may be prescribed Solu-Medrol. It is also given for gastrointestinal diseases, rheumatic disorders, endocrine disorders, neoplastic diseases, renal diseases, respiratory diseases, and hematologic disorders. Sometimes, it is prescribed for miscellaneous illnesses, like tuberculous meningitis and trichinosis.
When you are given a high dose of Solu-Medrol, it will take at least 30 minutes to administer the infusion. Then, you can receive a new dose every 4 to 6 hours for the next 48 hours. If you are receiving a high dose, you shouldn’t be given this infusion for more than 72 hours.
When you take Solu-Medrol for a longer period of time, your doctor will gradually taper off your dose. If you have multiple sclerosis (MS), you may be given a daily dose for a week followed by a dose every other day for a month.
Stelara IV & SQ
Manufacturer website:
https://www.stelarahcp.com/ulcerative-colitis/dosingCondition:
- Crohn’s Disease
- Plaque Psoriasis
- Psoriatic Arthritis
- Ulcerative Colitis
With Stelara, you initially receive an intravenous (IV) induction dose if you have ulcerative colitis or Crohn’s disease. Afterward, you will have a subcutaneous (SQ or subQ) maintenance dose every eight weeks. Your initial IV infusion will take at least an hour to complete.
The amount of medication you receive will depend on your body weight. Following your initial dose, you should receive six subcutaneous injection maintenance doses during the first year.
If you have plaque psoriasis or psoriatic arthritis, you will be given an IV dose at zero and four weeks. Afterward, your doses will happen every 12 weeks.
Stelara can change the way your immune system functions. Because of this, it can increase your chances of developing an infection. Latent infections can also be reactivated when you are on Stelara, so you should carefully discuss the risks and benefits of taking this treatment if you are currently suffering from an infection.
Sylvant
If you are suffering from multicentric Castleman's disease (MCD), Sylvant may be able to help. Recommended by the National Comprehensive Cancer Network, Sylvant is the only therapy currently approved by the Food and Drug Administration (FDA) for people who are negative for herpesvirus‑8 (HHV‑8) and human immunodeficiency virus (HIV). By neutralizing a cytokine known as interleukin-6 (IL-6), Sylvant can successfully prevent a cytokine storm from happening.
Getting an MCD diagnosis can be difficult. Normally, your lymph nodes are responsible for creating immune cells and fighting off infections. When you have MCD, your lymph nodes become swollen because there are too many of these immune cells.
Because you can experience so many different kinds of symptoms, it is hard to diagnose this disease right away. Without a diagnosis, you may eventually develop organ failure.
To take Sylvant, you must have a blood test to show you meet treatment parameters. This test will be performed before each treatment during the first 12 months. Afterward, you will be tested every three dosing cycles.
Your infusion will generally take about an hour to complete. You will get another infusion every three weeks until your treatments are no longer working.
Tecentriq
Manufacturer website:
https://www.tecentriq.com/Condition:
- Advanced Bladder Cancer
- Advanced Melanoma
- Extensive Stage Small Cell Lung Cancer
- Lung Cancer
- Non-Small Cell Lung Cancer
If you have lung cancer, melanoma, or bladder cancer, you may be a good candidate for Tecentriq. This cancer immunotherapy treatment can have different dosages and treatment schedules based on the type of cancer. For example, certain types of non-small cell lung cancers are treated with a three-step plan.
For stage 2 to stage 3A PD-L1+ non-small cell lung cancer, you would start by going through a surgery to remove the tumors. Afterward, you would kill off some of the remaining cancer cells through chemotherapy. Then, Tecentriq could be used to treat any cancer cells that remain.
Tecentriq is believed to work by reactivating your immune system. Once this happens, your body is able to recognize cancer cells in your body. Some types of cancer cells are talented at hiding from your immune system, so your body needs Tecentriq to help it learn how to identify and attack cancer cells on its own.
Tepezza
Tepezza can help you reduce double vision. It provides relief for multiple symptoms of thyroid eye disease. Other than helping with eye bulging, it can also decrease redness, swelling, and pain.
This intravenous (IV) medicine is generally given in a hospital, clinic, or infusion center. Normally, patients are given a total of eight infusions. The first two infusions will take about 90 minutes to complete.
After your first two infusions, the remaining infusions will take 60 minutes to complete. Because you will receive your infusions three weeks apart, it will take around five months to complete the entire course of treatment. Your doctor will determine how much Tepezza you receive based on your weight.
After each infusion you will be monitored for a period of time ranging from 30 to 60 minutes.
While you have already had eye exams to diagnose thyroid eye disease, your doctor will conduct another eye exam before you start treatment to see how this disease is affecting your eyes. Because Tepezza can increase your blood sugar, you may also need to have your blood sugar tested.
Truxima
Manufacturer website:
https://www.truxima.com/Condition:
- Chronic Lymphocytic Leukemia (CLL)
- Granulomatosis With Polyangiitis (GPA) (Wegener’s Granulomatosis)
- Microscopic Polyangiitis (MPA)
- Non-Hodgkin's Lymphoma (NHL)
- Rheumatoid Arthritis
Truxima is used to treat adults who have rheumatoid arthritis (RA), non-Hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), granulomatosis with polyangiitis (GPA), and microscopic polyangiitis (MPA). It consists of an antibody that targets white blood cells known as B cells.
These B cells normally help your body fight off infection. In RA and other diseases, they don’t function properly and begin attacking healthy tissues. Truxima can decrease the number of these B cells, which can help alleviate the symptoms of your disease.
Truxima is a kind of medication known as a biologic, which means it is produced from living cells. As a biosimilar, Truxima has a similar function and safety profile as Rituxan.
If you have GPA or MPA, the induction doses occur each week for four weeks. Afterward, you will receive an intravenous (IV) infusion every six months.
For RA, you will be given two doses with methotrexate and spaced two weeks apart. Then, you can repeat this course of treatment 24 weeks later.
Tysabri (TOUCH center certified)
Tysabri was created to treat relapsing multiple sclerosis (MS). In clinical studies, this drug decreased the number of relapses and slowed disability progression. It also decreased the number of new brain lesions.
When you take Tysabri, you will be enrolled in the TOUCH Prescribing Program. This allows your entire healthcare team to track your treatment and your risk of progressive multifocal leukoencephalopathy (PML).
You will be given this treatment over the course of an hour. Then, you will receive subsequent doses every four weeks. After your first 12 treatments, you will be observed for an hour afterward to see if you are exhibiting any signs of a hypersensitivity reaction. Once you have received 12 infusions and have had no reactions, you will not need monitoring.
While Tysabri is typically used for MS patients, it can also be used if you have Crohn’s disease. With Crohn’s disease, Tysabri can induce remission and help you maintain your remission.
Uplizna
Manufacturer website:
https://www.uplizna.com/Condition:
- Neuromyelitis Optica Spectrum Disorder (NMOSD)
If you suffer from neuromyelitis optica spectrum disorder (NMOSD), Uplizna is designed to help. Autoimmune diseases can cause inflammation in your central nervous system. Because of this, Uplizna relies on B cells for treating your disease.
B cells normally make antibodies to protect you from illnesses. With NMOSD, these B cells end up making autoantibodies to attack your central nervous system instead of targeting viruses like they are supposed to. By destroying B cells at all parts of their life cycle, Uplizna can prevent NMOSD attacks from happening.
Uplizna is typically taken in two doses. These doses are initially spaced two weeks apart. Afterward, you can take a maintenance dose every six months. Your infusion will be approximately 90 minutes.
During the first 28 weeks of the Uplizna study, almost 90% of patients managed to be attack free. Plus, hospitalization rates were reduced by 78%. While major side effects can occasionally happen, the most common side effects experienced were joint pain and urinary tract infections.
Vimizim
Vimizim is the only enzyme replacement therapy (ERT) approved to treat Morquio A. As a kind of mucopolysaccharidosis (MPS), Morquio A is essentially a rare lysosomal storage disorder. This genetic disease can cause your body to make too little of a special enzyme.
Without this enzyme, glycosaminoglycans (GAGs) can build up in your body. This can lead to issues with your major organs, tissues, and bones. Because it can affect each individual differently, your symptoms may not be the same as someone else who suffers from Vimizim.
Vimizim can help by replacing the enzymes your body lacks. By doing this, it can restore some of your cell function. Over time, it can improve your lung function and overall endurance.
Vimizim is typically taken as a weekly treatment. In general, you can expect your infusions to take around six hours to complete, this includes pre-medications. During the infusion, you will be monitored for infusion reactions and side effects.
VPRIV
VPRIV can be used over the long run as an enzyme replacement therapy (ERT) for people who have type 1 Gaucher disease. People who have this rare disorder suffer from a deficiency of glucocerebrosidase. Eventually, this deficiency can cause a fatty substance to develop in cells within your organs.
This fatty buildup can cause problems for your spleen, liver, and other tissues. While each person may experience different symptoms with type 1 Gaucher disease, many patients will suffer from low platelet levels, enlarged livers, low red blood cell counts, and enlarged spleens.
VPRIV can help you manage type 1 Gaucher disease. It uses the same amino sequence your body would normally make, so it can alleviate your symptoms.
Sometimes, people experience hypersensitivity and an allergic reaction to VPRIV. If this happens, you might experience dizziness, blood pressure changes, nausea, headaches, tiredness, fever, or weakness. Because more serious side effects are also possible, it is important to always work with a medical professional.
Vyepti
From your very first treatment, Vyepti can begin reducing the number of migraines you experience each month. If you suffer from at least four migraine days a month, Vyepti may be able to help. You can talk to your healthcare provider about whether this medication is the right choice for you.
Veyepti works by affecting calcitonin gene-related peptide (CGRP), which is a kind of protein. Scientists believe this protein may play a role in causing migraines. Because Vyepti can bind to CGRP, this protein is unable to activate receptors in your mind and cause migraines.
Each infusion lasts just 30 minutes. You will get four infusions a year. Following infusions, patients had an average of eight fewer migraines each month.
Vyepti causes very few side effects. In research studies, the most common side effects were stuffy nose, scratchy throats, and allergic reactions. Because this medication may not be safe from pregnant people, it is important to tell your doctor if you are currently pregnant or plan on becoming pregnant.
Vyvgart
Vyvgart is designed to treat people who are struggling with generalized myasthenia gravis (gMG). It uses a fragment of an immunoglobulin G IgG antibody to help people who have anti-AChR antibody positive gMG. In clinical trials, patients were able to improve their daily abilities and decrease their muscle weakness.
Once you start taking Vyvgart, it can decrease your IgG antibodies. This can prevent gMG symptoms from happening.
In clinical studies, many side effects were only slightly more common in the treatment group than in the control group. Taking Vyvgart can slightly increase the chances of respiratory tract infections, headaches, tingling sensations, muscle pain, and urinary tract infections.
Initially, your doctor will give you a one-hour infusion each week for four weeks. After the treatment cycle is over, your doctor will determine how long you can take a break until you go through another treatment cycle. On average, patients were able to go 72 days between treatment cycles.
Zemaira
If you have been diagnosed with an alpha-1 antitrypsin deficiency (A1AT), Zemaira may be able to help you manage your disease. Unlike other lung conditions, A1AT is a hereditary condition. This means it is passed from your parents to you through your genes.
Known as genetic chronic obstructive pulmonary disease (COPD), A1AT causes an estimated 3% of COPD cases. Like traditional COPD, it causes coughing, trouble breathing, and wheezing. Unlike other COPD cases, A1AT happens because your body doesn’t create enough A1AT to prevent inflammation from damaging your lungs.
Without proper treatment, this deficiency can end up causing emphysema and progressive lung damage. Because it can raise your level of alpha1-proteinase inhibitor, Zemaira can help to decrease your deficiency.
Most people can receive a Zemaira infusion in just 15 minutes. Your dosage can change based on your weight, so your infusion time can also vary. Afterward, you can start a weekly infusion schedule.
Zinplava
If you have struggled with recurrent Clostridium difficile (C. diff) infections, Zinplava could help. This medication was created for people who continue to have C. diff infections after taking antibiotics. Zinplava isn’t an antibiotic, so you shouldn’t try to replace your antibiotic medications with it.
This medication is made out of human monoclonal antibodies. These antibodies can bind with C. diff toxin B, which can help reduce the risk of your infection coming back. Zinplava is intended for people who are already on an antibacterial treatment and who have a high risk of another C. diff infection.
A single dose of Zinplava will take about 60 minutes to complete at the infusion center. It is only made to prevent infections, so you will need to take antibiotics to treat an active infection.
Some people may experience side effects during or after the infusion. If you experience high body temperature, nausea, headaches, or other adverse reactions, you should tell your infusion provider right away.
Zofran
Manufacturer website:
https://www.novartis.com/us-en/sites/novartis_us/files/zofran_inj_0.pdfCondition:
- Nausea Related to Chemotherapy
- Postoperative Nausea
If you are undergoing a surgical procedure or chemotherapy, your doctor may prescribe an infusion of Zofran. This medication can reduce nausea and vomiting associated with chemotherapy. It can also help reduce postoperative nausea and vomiting.
For chemotherapy, you will receive your first dose 30 minutes before you start your treatment. Afterward, you will receive your additional treatments four hours and eight hours later.
For postoperative nausea, the medication is given to adults and children over the age of 12 over the course of 30 seconds to five minutes. Children between the age of 1 month and 12 years can receive a smaller dose based on their weight.
While side effects only happen in a fraction of patients, you could experience symptoms. The most common side effects were tiredness, headache, diarrhea, and fever. If you experience any of these side effects, tell your doctor or infusion provider right away.
Collaboration Across the Continuum of Care
